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TisXell Regeneration System  »  TisXell Regeneration System
TisXell Regeneration System
Quinxell Technologies Pte Ltd.
Product information

QuinXell’s novel TisXell Regeneration System offers a favourable environment for high growth and high proliferation of cell cultures compared to conventional methods. The biaxial bioreactor controlled environment provides optimal nutrients and gases to growing cells and triggers cellular mechano-transduction signalling pathways to stimulate tissue remodelling onto a three dimensional (3D) scaffold. Our integrated solution comprising TisXell Regeneration System and  scaffolds addresses tissue engineering applications with unsurpassed performance especially for slow growing cells like bone cells, stem cells and primary cells.

Unique Features

  • Patented biaxial revolution in two independent orthogonal axes (spin and tumble simultaneously)
  • Flexible operational modes available – biaxial, uniaxial, swing modes
  • Efficient fluid transport within the 3D scaffolds, allowing optimal nutrients and waste exchange to and from the cells, penetrating the deepest core of the scaffolds
  • Spherical design of vessel creates a biaxial flow regime that is highly laminar and conducive for growing cells in 3D constructs

Key Benefits

  • Accelerates cell growth, differentiation and cell proliferation, mimicking native extracellular matrix (ECM)
  • Supports homogenous cell culture at the surface and core of the 3D scaffolds
  • Maintains functionality and viability of tissue constructs
  • Reduces formation of necrotic neo-tissue that interferes with subsequent implantation process
  • Promotes integration of implants with surrounding tissue and support the structural integrity in regeneration of tissues and/or organs

Innovative Design

  • Independently controlled drive axes for biaxial revolution, single axis or swing modes
  • Continuous perfusion with integrated selectable speed peristaltic pump (flow rates from 3 to 500 ml/min)
  • Oxygenator unit to facilitate gaseous exchange
  • 6-port medium reservoir with sensor bank (for optional temperature, pH, oxygen probes)
  • Heat isolated system drivers and controller in a separate console
  • System may be placed in a CO2 incubator when desired


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